Researchers find CRISPR is capable of even more than we thought
Newly discovered weapons of bacterial self-defense take different approaches to achieving the same goal: preventing a virus from spreading through the bacterial population.
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Individual layers of synthetic materials can collaborate for greater impact
Millions of years of evolution have enabled some marine animals to grow complex protective shells composed of multiple layers that work together to dissipate physical stress. In a new study, engineers have found a way to mimic the behavior of this type of layered material, such as seashell nacre, by programming individual layers of synthetic material to work collaboratively under stress. The new material design is poised to enhance energy-absorbing systems such as wearable bandages and car bumpers with multistage responses that adapt to collision severity.
New research details how infrared thermography, high-definition imaging and neural network analysis can combine to make concrete bridge inspections more efficient. Researchers are hopeful that their findings can be leveraged by engineers through a combination of these methods to strategically pinpoint bridge conditions and better allocate repair costs.
AI-powered app enables anemia screening using fingernail selfies
A groundbreaking new study introduces an AI-powered smartphone app that noninvasively screens for anemia using a photo of a user's fingernail. The study shows the app provides hemoglobin estimates comparable to traditional lab tests, with over 1.4 million tests conducted by 200,000+ users. An estimated 83 million Americans and more than 2 billion people globally are at high risk for anemia -- populations that stand to benefit significantly from this accessible screening tool. The app offers a low-cost, scalable solution that enhances access, especially in underserved and remote communities, while enabling real-time health monitoring and earlier intervention.
Designing the future of clean energy: Janus heterobilayers lead the way
Janus heterobilayers -- dual-sided materials with unique properties -- may be the key to efficiently creating clean hydrogen fuels.
Hazardous reactions made safer through flow technology
Researchers have designed a high-performance, open-access continuous flow process to safely produce key antibacterial drugs from bio-based furfural.
New model for more accurate landslide prediction
Engineers have developed a groundbreaking computational model to study the movement of granular materials such as soils, sands and powders. By integrating the dynamic interactions among particles, air and water phases, this state-of-the-art system can accurately predict landslides, improve irrigation and oil extraction systems, and enhance food and drug production processes.
New auditory brainstem implant shows early promise
Investigators are developing a new type of auditory brainstem implant that is designed to be soft, and flexible and address limitations of models currently in use. These implants may one day benefit people who can't receive a cochlear implant, such as those with Neurofibromatosis type 2 (NF2) and other severe inner ear abnormalities. In a new preclinical study, researchers report on benefits in large animal models, and based on the results, hope for future trials in humans.
Log in to your computer with a secret message encoded in a molecule
Molecules like DNA are capable of storing large amounts of data without requiring an energy source, but accessing this molecular data is expensive and time consuming. Researchers have now developed an alternative method to encode information in synthetic molecules, which they used to encode and then decode an 11-character password to unlock a computer.
New gene editor enables greater precision
A new gene editor may soon open the door to gene therapies for a wider array of diseases.
New insights into quantum physics
A new study explores how EOS transmits ultrashort laser pulses through crystals that change in response to an applied electric field. This technique allows researchers to accurately capture the shape and timing of electric fields across a broad range of frequencies.
Bismuth's mask uncovered: Implications for quantum computing and spintronics materials
Whether bismuth is part of a class of materials highly suitable for quantum computing and spintronics was a long-standing issue. Research has now revealed that the true nature of bismuth was masked by its surface, and in doing so uncovered a new phenomenon relevant to all such materials.
Ultraviolet data from NASA's Europa Clipper mission
The Ultraviolet Spectrograph (UVS) aboard NASA's Europa Clipper spacecraft has successfully completed its initial commissioning following the October 14, 2024, launch. Scheduled to arrive in the Jovian system in 2030, the spacecraft will orbit Jupiter and ultimately perform repeated close flybys of the icy moon Europa. Previous observations show strong evidence for a subsurface ocean of liquid water that could host conditions favorable for life.
Learning as an adventure: The lecture theater in the spaceship
In Project Chimera, a game lab combines a VR computer game with educational problems in order to convey scientific content in a motivating way.
Hexagons for data protection: Proof of location without disclosing personal data
Location data is considered particularly sensitive -- its misuse can have serious consequences. Researchers have now developed a method that allows individuals to cryptographically prove their location -- without revealing it. The foundation of this method is the so-called zero-knowledge proof with standardized floating-point numbers.
AI overconfidence mirrors human brain condition
Agents, chatbots and other tools based on artificial intelligence (AI) are increasingly used in everyday life by many. So-called large language model (LLM)-based agents, such as ChatGPT and Llama, have become impressively fluent in the responses they form, but quite often provide convincing yet incorrect information. Researchers draw parallels between this issue and a human language disorder known as aphasia, where sufferers may speak fluently but make meaningless or hard-to-understand statements. This similarity could point toward better forms of diagnosis for aphasia, and even provide insight to AI engineers seeking to improve LLM-based agents.
A novel hybrid charge transfer crystal with reversible color-changing property
Charge transfer, or the movement of electrons, can occur either within a molecule or between two molecules. Combining the two types of charge transfer is challenging. Now, scientists have developed a hybrid charge transfer crystal using a novel pyrazinacene molecule. This crystal is capable of reacting with naphthalene to produce a reversible color shift, from greenish-blue to red-violet. Such color-changing crystals can have various potential applications in materials science.
New dual-atom catalyst boosts performance of zinc-air batteries for real-world applications
A research team has unveiled a breakthrough in improving the performance of zinc-air batteries (ZABs), which are an important energy storage technology. This breakthrough involves a new catalyst that significantly boosts the efficiency of the oxygen reduction reaction (ORR), a crucial process in ZABs. The development could lead to more efficient, long-lasting batteries for practical applications.
Researchers develop new metallic materials using data-driven frameworks and explainable AI
Found in knee replacements and bone plates, aircraft components, and catalytic converters, the exceptionally strong metals known as multiple principal element alloys (MPEA) are about to get even stronger through to artificial intelligence. Scientists have designed a new MPEA with superior mechanical properties using a data-driven framework that leverages the supercomputing power of explainable artificial intelligence (AI).
Seeing blood clots before they strike
Researchers have found a way to observe clotting activity in blood as it happens -- without needing invasive procedures. Using a new type of microscope and artificial intelligence (AI), their study shows how platelet clumping can be tracked in patients with coronary artery disease (CAD), opening the door to safer, more personalized treatment.
Research reveals why next-generation engine noise grinds our gears
A breakthrough study has revealed why emerging electric aircraft engine technology sounds so annoying -- and how to fix it.
A multitude of protoplanetary discs detected in the galactic centre
Using new observations with the ALMA telescope array in Chile, researchers have compiled the most precise map of three regions in the Milky Way's Central Molecular Zone to date, providing valuable information on how stars form in that region.
Cyberbullying in any form can be traumatizing for kids
New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms. Indirect harassment was most common, with more than half reporting hurtful comments, rumors or deliberate exclusion. What mattered most was the overall amount of cyberbullying: the more often a student was targeted, the more trauma symptoms they showed.
Focused ultrasound halts growth of debilitating brain lesions
A new, incision-free technique developed at UVA Health to treat debilitating brain lesions called cerebral cavernous malformations, or cavernomas, has shown great promise in early testing, halting the growth of the lesions almost entirely.
Stretched in a cross pattern: Our neighboring galaxy is pulled in two axes
Researchers have discovered that Cepheid variable stars in our neighboring galaxy, the Small Magellanic Cloud, are moving in opposing directions along two distinct axes. They found that stars closer to Earth move towards the northeast, while more distant stars move southwest. This newly discovered movement pattern exists alongside a northwest-southeast opposing movement that the scientists previously observed in massive stars.
As industries seek innovative solutions for carbon capture, scientists have turned to advanced materials that efficiently trap and store carbon dioxide (CO ) from industrial emissions. A recent study sheds light on the gas adsorption physics of so-called Calgary Framework 20 (CALF-20), a zinc-based metal-organic framework (MOF). While applying a combination of advanced techniques, the scientists reveal the material's unique adaptability under varying conditions.
Researchers have developed a simple method to explore a complex area of quantum science. The discovery makes research in this field cheaper and more accessible, which could significantly impact the development of future laser, quantum and high-tech display technologies.
New study offers insights into designing safe, effective nasal vaccines
Most vaccines -- and boosters -- are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease. But for respiratory diseases like COVID-19, it can be important to have protection right where the virus enters: the respiratory tract. In a new study, researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.
Successful experiments at GSI/FAIR uncover new island of asymmetric fission
An international team of scientists has identified an unexpected region of heavy, neutron-deficient isotopes in the nuclear chart where nuclear fission is predominantly governed by an asymmetric mode.
Drinking water, select foods linked to PFAS in California adults
A new study examined associations between diet, drinking water, and 'legacy' PFAS -- chemicals that were phased out of production in the US in the 2000s -- with blood samples from California residents. PFAS exposure was associated with consumption of seafood, eggs, and brown rice, but fewer other foods than suggested by earlier studies. PFAS levels were elevated among people who lived in areas where these chemicals were detectable in their drinking water supply, but lower than levels found in highly contaminated communities.
Superconductors: Amazingly orderly disorder
A surprising connection has been found, between two seemingly very different classes of superconductors. In a new material, atoms are distributed irregularly, but still manage to create long-range magnetic order.
Professor challenges long-held assumptions of symmetry in physics
A groundbreaking experiment--reveals 'symmetry' in physics doesn't always behave as scientists once believed.
Engineers tackle sunlight intermittency in solar desalination
A team of engineers has developed a system that could transform desalination practices, making the process more adaptable, resilient and cheaper. The new system is powered by sunlight and uses a creative approach to heat recovery for extended water production -- with and without sunshine.
What lies beneath: Using rock blasted from craters to probe the Martian subsurface
By analyzing how far material ejected from an impact crater flies, scientists can locate buried glaciers and other interesting subsurface features.
Following the folds -- with quantum technology
The connection between a crumpled sheet of paper and quantum technology: A research team at the EPFL in Lausanne (Switzerland) and the University of Konstanz (Germany) uses topology in microwave photonics to make improved systems of coupled cavity arrays.
Satellite data from ship captures landslide-generated tsunami
New research demonstrates shipborne navigation systems have potential to improve tsunami detection and warning.
Traditional methods of assessing damage after a disaster can take weeks or even months, delaying emergency response, insurance claims and long-term rebuilding efforts. New research might change that. Researchers have developed a new method that combines remote sensing, deep learning and restoration models to speed up building damage assessments and predict recovery times after a tornado. Once post-event images are available, the model can produce damage assessments and recovery forecasts in less than an hour.
Study shows vision-language models can't handle queries with negation words
Researchers found that vision-language models, widely used to analyze medical images, do not understand negation words like 'no' and 'not.' This could cause them to fail unexpectedly when asked to retrieve medical images that contain certain objects but not others.
New nanoparticle could make cancer treatment safer, more effective
Scientists have created a new nanoparticle that could make ultrasound-based cancer treatments more effective and safer, while also helping prevent tumors from coming back. To make the therapy even more powerful, the scientists also attached a potent chemotherapy drug to the peptide on the nanoparticle's surface. The ultrasound physically destroys the tumor, and the drug helps eliminate any leftover cancer cells that might cause the tumor to return.
Artificial intelligence and genetics can help farmers grow corn with less fertilizer
Scientists are using artificial intelligence to determine which genes collectively govern nitrogen use efficiency in plants such as corn, with the goal of helping farmers improve their crop yields and minimize the cost of nitrogen fertilizers.
Energy and memory: A new neural network paradigm
Listen to the first notes of an old, beloved song. Can you name that tune? If you can, congratulations -- it's a triumph of your associative memory, in which one piece of information (the first few notes) triggers the memory of the entire pattern (the song), without you actually having to hear the rest of the song again. We use this handy neural mechanism to learn, remember, solve problems and generally navigate our reality.
How we think about protecting data
A new game-based experiment sheds light on the tradeoffs people are willing to make about data privacy.
The key to spotting dyslexia early could be AI-powered handwriting analysis
A new study outlines how artificial intelligence-powered handwriting analysis may serve as an early detection tool for dyslexia and dysgraphia among young children.
Handy octopus robot can adapt to its surroundings
Scientists inspired by the octopus's nervous system have developed a robot that can decide how to move or grip objects by sensing its environment.
'Sweet spot' for focused ultrasound to provide essential tremor relief
For millions of people around the world with essential tremor, everyday activities from eating and drinking to dressing and doing basic tasks can become impossible. This common neurological movement disorder causes uncontrollable shaking, most often in the hands, but it can also occur in the arms, legs, head, voice, or torso. Essential tremor impacts an estimated 1 percent of the worldwide population and around 5 percent of people over 60. Investigators have now identified a specific subregion of the brain's thalamus that, when included during magnetic resonance-guided focused ultrasound (MRgFUS) treatment, can result in optimal and significant tremor improvements while reducing side effects.
MRI scans could help detect life-threatening heart disease
Magnetic resonance imaging (MRI) scans of the heart could help to detect a life-threatening heart disease and enable clinicians to better predict which patients are most at risk, according to a new study.
New study shows AI can predict child malnutrition, support prevention efforts
A multidisciplinary team of researchers has developed an artificial intelligence (AI) model that can predict acute child malnutrition in Kenya up to six months in advance. The tool offers governments and humanitarian organizations critical lead time to deliver life-saving food, health care, and supplies to at-risk areas. The machine learning model outperforms traditional approaches by integrating clinical data from more than 17,000 Kenyan health facilities with satellite data on crop health and productivity. It achieves 89% accuracy when forecasting one month out and maintains 86% accuracy over six months -- a significant improvement over simpler baseline models that rely only on recent historical child malnutrition prevalence trends.
Dark matter formed when fast particles slowed down and got heavy, new theory says
Researchers propose a new theory for the origin of dark matter, the invisible substance thought to give the universe its shape and structure. Their mathematical models show that dark matter could have formed in the early universe from the collision of massless particles that lost their energy and condensed -- like steam turning into water -- into cold, heavy particles. They report that their theory can be tested using existing data -- these dark matter particles would have a unique signature on the radiation that fills all of the universe known as the Cosmic Microwave Background.
New generation of skin substitutes give hope to severe burns patients
Australian researchers have flagged some promising new approaches to treat severe burns that could save lives and dramatically improve patient recovery.
Digital lab for data- and robot-driven materials science
Researchers have developed a digital laboratory (dLab) system that fully automates the material synthesis and structural, physical property evaluation of thin-film samples. With dLab, the team can autonomously synthesize thin-film samples and measure their material properties. The team's dLab system demonstrates advanced automatic and autonomous material synthesis for data- and robot-driven materials science.
Got data? Breastfeeding device measures babies' milk intake in real time
New device can give peace of mind and reduce anxiety for breastfeeding moms. It uses bioimpedance, which is currently used to measure body fat, and streams clinical-grade data to a smartphone or tablet in real time. Developed by physicians and engineers, device was tested by new moms. Technology could particularly benefit fragile babies in the NICU, who have precise nutritional needs.
New hope against superbugs: Promising antibiotic candidate discovered
An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.
Sugar-coated nanotherapy dramatically improves neuron survival in Alzheimer's model
In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into nanofibers, which bond to the neuron-killing proteins. Now trapped, the toxic proteins can no longer enter neurons and instead harmlessly degrade.
Uncovering compounds that tame the heat of chili peppers
When biting into a chili pepper, you expect a fiery sensation on your tongue. This spiciness is detected because of capsaicinoid compounds. But for some peppers, despite high levels of capsaicinoids, the heat is mysteriously dull. Now, researchers have identified three compounds that lessen peppers' pungency. These results challenge the reliability of the century-old Scoville scale, which traditionally bases its rating on two capsaicinoids.
Astronomers take a second look at twin star systems
Apples-to-apples comparisons in the distant universe are hard to come by. Whether the subject is dwarf galaxies, supermassive black holes, or 'hot Jupiters,' astronomers can spend months or years searching for comparable objects and formations to study. And it is rarer still when those objects are side-by-side. But a new study offers a road map for finding 'twin' planetary systems -- showing whether binary stars that orbit each other, and that were born at the same time and place, tend to host similar orbiting planets. The study's authors found that certain orientations of twin star systems may provide critical information about planet formation, while also being easier for astronomers to discover planets within the systems.
Making connections: A three-dimensional visualization of musculoskeletal development
Using a new fluorescent mouse model with advanced imaging techniques, researchers have successfully visualized how musculoskeletal components are integrated into the functional locomotor system during embryonic development.
New insights into black hole scattering and gravitational waves unveiled
A new study achieves unprecedented accuracy in modelling extreme cosmic events like black hole and neutron star collisions by calculating the fifth post-Minkowskian (5PM) order, crucial for interpreting gravitational wave data from current and future observatories. The research reveals the surprising appearance of Calabi-Yau three-fold periods -- complex geometric structures from string theory and algebraic geometry -- within calculations of radiated energy and recoil, suggesting a deep connection between abstract mathematics and astrophysical phenomena. Utilizing over 300,000 core hours of high-performance computing, an international team demonstrated the power of advanced computational methods in solving complex equations governing black hole interactions, paving the way for more accurate gravitational wave templates and insights into galaxy formation.
Scientists have successfully relocated protons outside of an antimatter laboratory with the help of an autonomous, open Penning trap. This breakthrough marks a significant step toward transporting antiprotons produced at the European Organization for Nuclear Research (CERN) to high-precision laboratories, which operate independently of the research facility. Extremely precise measurements to compare matter and antimatter are only possible far from accelerator facilities.
New catalyst boosts efficiency of CO2 conversion
Researchers have developed an encapsulated cobalt-nickel alloy that significantly improves the efficiency and durability of high-temperature CO2 conversion, a promising technology for carbon recycling and sustainable fuel production.
New computer language helps spot hidden pollutants
Biologists and chemists have a new programming language to uncover previously unknown environmental pollutants at breakneck speed -- without requiring them to code.