In healthy aging, carb quality counts
Intakes of dietary fiber and high-quality carbohydrates in midlife are linked to increased likelihood of healthy aging and other positive health outcomes in older women. Higher intakes of refined carbohydrates and starchy vegetables were associated with lower odds of healthy aging.
Researchers find CRISPR is capable of even more than we thought
Newly discovered weapons of bacterial self-defense take different approaches to achieving the same goal: preventing a virus from spreading through the bacterial population.
Study reveals healing the ozone hole helps the Southern Ocean take up carbon
New research suggests that the negative effects of the ozone hole on the carbon uptake of the Southern Ocean are reversible, but only if greenhouse gas emissions rapidly decrease. The study finds that as the ozone hole heals, its influence on the ocean carbon sink of the Southern Ocean will diminish, while the influence of greenhouse gas (GHG) emissions will rise.
Overlooked cell type orchestrates brain rewiring
Researchers have shown in mice that brain cells known as astrocytes are required for a signaling chemical called norepinephrine to modify brain activity, changing the textbook understanding that norepinephrine acts directly on neurons.
One in ten asthma cases can be avoided with a better urban environment
The combination of air pollution, dense urban development and limited green spaces increases the risk of asthma in both children and adults.
Rising temperatures lead to unexpectedly rapid carbon release from soils
How sensitively does organic carbon stored in soils react to changes in temperature and humidity?
New research from an international group looking at ancient sediment cores in the North Atlantic has for the first time shown a strong correlation between sediment changes and a marked period of global cooling that occurred in the Northern Hemisphere some 3.6 million years ago. The changes in sediments imply profound changes in the circulation of deep water currents occurred at this time. This crucial piece of work, which showed sediments changed in multiple sites east of the mid-Atlantic ridge but not west of that important geographical feature, opens multiple doors to future research aimed at better understanding the link between deep water currents, Atlantic Ocean heat and salt distribution and ice-sheet expansion, and climatic change.
Wild orangutans show communication complexity thought to be uniquely human
Researchers have found that wild orangutans vocalize with a layered complexity previously thought to be unique to human communication, suggesting a much older evolutionary origin.
New auditory brainstem implant shows early promise
Investigators are developing a new type of auditory brainstem implant that is designed to be soft, and flexible and address limitations of models currently in use. These implants may one day benefit people who can't receive a cochlear implant, such as those with Neurofibromatosis type 2 (NF2) and other severe inner ear abnormalities. In a new preclinical study, researchers report on benefits in large animal models, and based on the results, hope for future trials in humans.
Log in to your computer with a secret message encoded in a molecule
Molecules like DNA are capable of storing large amounts of data without requiring an energy source, but accessing this molecular data is expensive and time consuming. Researchers have now developed an alternative method to encode information in synthetic molecules, which they used to encode and then decode an 11-character password to unlock a computer.
Very different mammals follow the same rules of behavior
In the natural world -- where predators pounce, prey flee, and group members feed and sleep in solidarity -- animal behavior is glorious in its variety. Now, new research suggests there may be an underlying architecture that orders the movements of animals as they go about their very different lives. And it's more widespread than previously imagined.
New gene editor enables greater precision
A new gene editor may soon open the door to gene therapies for a wider array of diseases.
Bismuth's mask uncovered: Implications for quantum computing and spintronics materials
Whether bismuth is part of a class of materials highly suitable for quantum computing and spintronics was a long-standing issue. Research has now revealed that the true nature of bismuth was masked by its surface, and in doing so uncovered a new phenomenon relevant to all such materials.
Study reveals a deep brain region that links the senses
Humans perceive and navigate the world around us with the help of our five senses: sight, hearing, touch, taste and smell. And while scientists have long known that these different senses activate different parts of the brain, a new study indicates that multiple senses all stimulate a critical region deep in the brain that controls consciousness. The study sheds new light on how sensory perception works in the brain and may fuel the development of therapies to treat disorders involving attention, arousal, and consciousness.
Ultraviolet data from NASA's Europa Clipper mission
The Ultraviolet Spectrograph (UVS) aboard NASA's Europa Clipper spacecraft has successfully completed its initial commissioning following the October 14, 2024, launch. Scheduled to arrive in the Jovian system in 2030, the spacecraft will orbit Jupiter and ultimately perform repeated close flybys of the icy moon Europa. Previous observations show strong evidence for a subsurface ocean of liquid water that could host conditions favorable for life.
Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven't worked -- largely because HIV mutates rapidly and hides key parts of itself from the immune system. Now, a new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them -- a key step toward a long-sought goal in vaccine development.
An international genomics study has revealed that early Asians undertook humanity's longest known prehistoric migration. These early humans, who roamed the earth over 100,000 years ago, are believed to have traveled more than 20,000 kilometers on foot from North Asia to the southernmost tip of South America. Scientists have mapped the unexpectedly vast genetic diversity of Asians, who make up more than half of the world's population. These findings overturn long-held assumptions of European genetic dominance and show that native South Americans are of Asian descent. The study also sheds light on how such a vast migration and differing environments have shaped human evolution, including how populations have adapted to diseases and how their immune systems have evolved.
Impact of oft-overlooked cell in brain function revealed
An often-ignored type of cell in the brain plays a dynamic and surprisingly complex role in our ability to process information, according to new research.
World's largest bat organoid platform paves the way for pandemic preparedness
Until now, most research has used either generalized cell samples or organoids made from just one type of tropical fruit bat, and only from a single organ. But a breakthrough has arrived: a research team has now created the world's most comprehensive bat organoid platform. These 'mini-organs' are grown from five common bat species found across Asia and Europe and represent four different organs -- airway, lungs, kidneys, and small intestine.
Key player in childhood food allergies identified: Thetis cells
Thetis cells, a class of immune cells first described in 2022, play an essential and previously unknown role in suppressing inflammatory responses to food, a new study finds.
The effect of physical fitness on mortality is overestimated
That fit people have a reduced risk of premature death from various diseases is a recurring result in many studies. New research shows that people with high fitness levels in their late teens also have a reduced risk of dying from random accidents. This suggests that the associations seen in previous studies have probably been misleading.
AI overconfidence mirrors human brain condition
Agents, chatbots and other tools based on artificial intelligence (AI) are increasingly used in everyday life by many. So-called large language model (LLM)-based agents, such as ChatGPT and Llama, have become impressively fluent in the responses they form, but quite often provide convincing yet incorrect information. Researchers draw parallels between this issue and a human language disorder known as aphasia, where sufferers may speak fluently but make meaningless or hard-to-understand statements. This similarity could point toward better forms of diagnosis for aphasia, and even provide insight to AI engineers seeking to improve LLM-based agents.
Researchers develop new metallic materials using data-driven frameworks and explainable AI
Found in knee replacements and bone plates, aircraft components, and catalytic converters, the exceptionally strong metals known as multiple principal element alloys (MPEA) are about to get even stronger through to artificial intelligence. Scientists have designed a new MPEA with superior mechanical properties using a data-driven framework that leverages the supercomputing power of explainable artificial intelligence (AI).
A multitude of protoplanetary discs detected in the galactic centre
Using new observations with the ALMA telescope array in Chile, researchers have compiled the most precise map of three regions in the Milky Way's Central Molecular Zone to date, providing valuable information on how stars form in that region.
Recessive genes are subject to Darwinian selection
As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring. This disadvantage is greatest for carriers of a recessive gene for intellectual disability, and reflected in a shorter school career and increased childlessness, according to new research. Time to rewrite the textbooks?
Dual associations with two fungi improve tree fitness
When trees and soil fungi form close associations with each other, both partners benefit. Many tree species have further enhanced this cooperation by forming a concurrent symbiosis with two different groups of mycorrhizal fungi. Those trees cope better with water and nutrient scarcity, which is an important trait for forestry in the face of climate warming.
World's rivers remapped to improve flood modeling
A team has created the most complete map of the world's rivers ever made offering a major leap forward for flood prediction, climate risk planning, and water resource management in a warming world. The new study introduces GRIT -- a mapping system that finally shows how rivers really flow, branch, and connect landscapes.
Cyberbullying in any form can be traumatizing for kids
New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms. Indirect harassment was most common, with more than half reporting hurtful comments, rumors or deliberate exclusion. What mattered most was the overall amount of cyberbullying: the more often a student was targeted, the more trauma symptoms they showed.
Human activity reduces plant diversity hundreds of kilometers away
Natural ecosystems comprise groups of species capable of living in the specific conditions of a biological system. However, if we visit a specific natural area, we will not find all the species capable of living in it. The proportion of species that could live in a specific location but do not do so is known as dark diversity, a concept coined in 2011. Research has now discovered that this dark diversity increases in regions with greater human activity.
Stretched in a cross pattern: Our neighboring galaxy is pulled in two axes
Researchers have discovered that Cepheid variable stars in our neighboring galaxy, the Small Magellanic Cloud, are moving in opposing directions along two distinct axes. They found that stars closer to Earth move towards the northeast, while more distant stars move southwest. This newly discovered movement pattern exists alongside a northwest-southeast opposing movement that the scientists previously observed in massive stars.
Scientists track down mutation that makes orange cats orange
Many an orange cat-affiliated human will vouch for their cat's, let's say, specialness. But now scientists have confirmed that there is, in fact, something unique about ginger-hued domestic felines. In a new study, researchers have discovered the long-posited but elusive genetic mutation that makes orange cats orange -- and it appears to occur in no other mammal.
Digital reconstruction reveals 80 steps of prehistoric life
A dinosaur's 40-second journey more than 120 million years ago has been brought back to life by a research team using advanced digital modelling techniques.
A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment. The process, from diagnosis to treatment, took only six months and marks the first time the technology has been successfully deployed to treat a human patient. The technology used in this study was developed using a platform that could be tweaked to treat a wide range of genetic disorders and opens the possibility of creating personalized treatments in other parts of the body.
New study finds that tea and chocolate may help lower blood pressure
We might have another reason to enjoy our daily cup of tea or small piece of dark chocolate, as a new study has found that naturally occurring compounds called flavan-3-ols -- found in cocoa, tea, apples and grapes -- may improve blood pressure and the health of our blood vessels.
New study reveals our skin's own bacteria can help protect us from the bad effects of sunlight
The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase. This enables the skin's ability to fine-tune how it responds to UV radiation. The findings demonstrate the ability of the skin microbiome to remodel host immune functions.
Should we protect non-native species? A new study says maybe
A new study found that over a quarter of the world's naturalized plant species are threatened in parts of their native range -- raising questions about the role non-native populations may play in global conservation efforts.
Too much sleep can hurt cognitive performance, especially for those with depression
Sleeping nine hours or more per night is associated with worse cognitive performance, and it is even more the case for those with depression.
What behavioral strategies motivate environmental action?
A collaborative study tested 17 strategies in an 'intervention tournament.' Interventions targeting future thinking, such as writing a letter for a child to read in the future, are the most effective ways to motivate climate action.
Brain scans reveal what happens in the mind when insight strikes
That 'aha' moment when you come back to a puzzle and immediately figure it out? Something fascinating is going on in your brain. A new study using functional magnetic resonance imaging shows that these flashes of insight aren't just satisfying -- they create strong memories that can help etch learning into the brain.
Marsupial research reveals how mammalian embryos form
Researchers have revealed insight into why embryos erase a key epigenetic mark during early development, suggesting this may have evolved to help form a placenta.
Research shows how hormone can reverse fatty liver disease in mice
A pioneering research study details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to improve liver function.
The increasing frequency of once-in-a-decade agricultural and ecological drought has underscored the urgency of studying hydrological changes. A research team has analyzed the estimated changes in land water storage over the past 40 years by utilizing space geodetic observation technology and global hydrological change data. This innovative method has revealed a rapid depletion in global soil moisture, resulting in a significant amount of water flowing into the oceans, leading to a rise in sea levels. The research provides new insights into the driving factors behind the alarming reduction in terrestrial water storage and rise in sea levels.
The key to spotting dyslexia early could be AI-powered handwriting analysis
A new study outlines how artificial intelligence-powered handwriting analysis may serve as an early detection tool for dyslexia and dysgraphia among young children.
Dexterity and climbing ability: how ancient human relatives used their hands
Scientists have found new evidence for how our fossil human relatives in South Africa may have used their hands. Researchers investigated variation in finger bone morphology to determine that South African hominins not only may have had different levels of dexterity, but also different climbing abilities.
Handy octopus robot can adapt to its surroundings
Scientists inspired by the octopus's nervous system have developed a robot that can decide how to move or grip objects by sensing its environment.
Fossil tracks show reptiles appeared on Earth up to 40 million years earlier
The origin of reptiles on Earth has been shown to be up to 40 million years earlier than previously thought -- thanks to evidence discovered at an Australian fossil site that represents a critical time period. Scientists have identified fossilized tracks of an amniote with clawed feet -- most probably a reptile -- from the Carboniferous period, about 350 million years ago.
Dark matter formed when fast particles slowed down and got heavy, new theory says
Researchers propose a new theory for the origin of dark matter, the invisible substance thought to give the universe its shape and structure. Their mathematical models show that dark matter could have formed in the early universe from the collision of massless particles that lost their energy and condensed -- like steam turning into water -- into cold, heavy particles. They report that their theory can be tested using existing data -- these dark matter particles would have a unique signature on the radiation that fills all of the universe known as the Cosmic Microwave Background.
Genome of near-extinct northern white rhino offers hope for reviving the species
The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino. This represents a crucial step toward bringing the critically endangered species back from the edge using advanced reproductive technologies. The complete genome can be used as a reference to analyze the health of previously developed northern white rhinoceros stem cells. Eventually, those stem cells may be able to generate sperm and eggs to yield new rhinos.
Astronomers take a second look at twin star systems
Apples-to-apples comparisons in the distant universe are hard to come by. Whether the subject is dwarf galaxies, supermassive black holes, or 'hot Jupiters,' astronomers can spend months or years searching for comparable objects and formations to study. And it is rarer still when those objects are side-by-side. But a new study offers a road map for finding 'twin' planetary systems -- showing whether binary stars that orbit each other, and that were born at the same time and place, tend to host similar orbiting planets. The study's authors found that certain orientations of twin star systems may provide critical information about planet formation, while also being easier for astronomers to discover planets within the systems.
Australia's oldest prehistoric tree frog hops 22 million years back in time
Scientists have now discovered the oldest ancestor for all the Australian tree frogs, with distant links to the tree frogs of South America.
Why are urban children more prone to allergies?
Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.
An ink that boosts coral reef settlement by 20 times
With coral reefs in crisis due to climate change, scientists have engineered a bio-ink that could help promote coral larvae settlement and restore these underwater ecosystems before it's too late. Researchers demonstrate that the ink could boost coral settlement by more than 20 times, which they hope could contribute to rebuilding coral reefs around the world.
New insights into black hole scattering and gravitational waves unveiled
A new study achieves unprecedented accuracy in modelling extreme cosmic events like black hole and neutron star collisions by calculating the fifth post-Minkowskian (5PM) order, crucial for interpreting gravitational wave data from current and future observatories. The research reveals the surprising appearance of Calabi-Yau three-fold periods -- complex geometric structures from string theory and algebraic geometry -- within calculations of radiated energy and recoil, suggesting a deep connection between abstract mathematics and astrophysical phenomena. Utilizing over 300,000 core hours of high-performance computing, an international team demonstrated the power of advanced computational methods in solving complex equations governing black hole interactions, paving the way for more accurate gravitational wave templates and insights into galaxy formation.
Archaeopteryx is the fossil that clearly demonstrated Darwin's views. It's the oldest known fossil bird, and it helps show that all birds -- including the ones alive today -- emerged from dinosaurs. And while the first Archaeopteryx fossil was found more than 160 years ago, scientists are continuing to learn new things about this ancient animal. A set of feathers never before seen in this species help explain why it could fly when many of its non-bird dinosaur cousins could not.
How the brain allows us to infer emotions
Researchers have discovered how inferred emotions are learned. The study shows that the frontal part of the brain coordinates with the amygdala -- a brain region important for simple forms of emotional learning -- to make this higher-order emotional ability possible. This breakthrough study is the first to show how the brain codes human-like internal models of emotion.
New global model shows how to bring environmental pressures back to 2015 levels by 2050
A new study finds that with bold and coordinated policy choices -- across emissions, diets, food waste, and water and nitrogen efficiency -- humanity could, by 2050, bring global environmental pressures back to levels seen in 2015. This shift would move us much closer to a future in which people around the world can live well within the Earth's limits.
Palaeontologists discover 506-million-year-old predator
Palaeontologists have discovered a remarkable new 506-million-year-old predator from the Burgess Shale of Canada. Mosura fentoni was about the size of your index finger and had three eyes, spiny jointed claws, a circular mouth lined with teeth and a body with swimming flaps along its sides. These traits show it to be part of an extinct group known as the radiodonts.
Not all orangutan mothers raise their infants the same way
Sumatran orangutan mothers differ from one another in how they behave with and take care of their infants and how flexibly they adjust their mothering behaviors as their infants grow. Whilst mothers differed from one another in their maternal behaviors, they remained consistent in their behaviors with their different infants. Consistent differences among Sumatran orangutan mothers suggest that individual maternal personalities may exist, potentially influencing infant development.
Eldercare robot helps people sit and stand, and catches them if they fall
Engineers built E-BAR, a mobile robot designed to physically support the elderly and prevent them from falling as they move around their homes. E-BAR acts as a set of robotic handlebars that follows a person from behind, allowing them to walk independently or lean on the robot's arms for support.
Researchers demonstrate 3-D printing technology to improve comfort, durability of 'smart wearables'
Imagine a T-shirt that could monitor your heart rate or blood pressure. Or a pair of socks that could provide feedback on your running stride. It may be closer than you think, with new research demonstrating a particular 3-D ink printing method for so-called smart fabrics that continue to perform well after repeated washings and abrasion tests.