ScienceDaily: All - September 14, 2024
Today's top research news
Experimental mRNA cancer vaccine shows potential for advanced stage cancer patients in Phase 1 trial
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers. The investigational mRNA cancer immunotherapy is targeted for patients with lung cancer, melanoma and other solid tumours. Nineteen patients with advanced stage cancers received between one and nine doses of the immunotherapy treatment. Scientists have found the immunotherapy created an immune response against cancer and was well tolerated, with adverse events including fatigue, injection site pain and fever.
Key factors that impact long-term weight loss in patients prescribed GLP-1 RA medications
A new study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity.
A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial, reinforce earlier findings of the benefits of the drug -- trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate -- in these patients, trial leaders say.
Babies born to pregnant women with obesity are more likely to develop heart problems and diabetes as adults due to fetal damage caused by the high-fat, high-energy diet of their mother.
Image: SNeG17/Shutterstock.com
CRISPR/Cas9 modifies euglena to create potential biofuel source
Through genome editing using CRISPR/Cas9, researchers stably create euglena mutants that can produce wax esters with improved cold flow, making the esters suitable as feedstock for biofuels.
Energy transmission in quantum field theory requires information
An international team of researchers has found a simple relationship between the rates of energy and information transmission across an interface connecting two quantum field theories.
Plant-derived secondary organic aerosols can act as mediators of plant-plant interactions
A new study reveals that plant-derived secondary organic aerosols (SOAs) can act as mediators of plant-plant interactions. This research was conducted through the cooperation of chemical ecologists, plant ecophysiologists and atmospheric physicists.
New proteins involved in regulating the cell membrane
Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating entry and exit of certain molecules to maintain a stable internal environment.
Exceptional warm air intrusions and omnipresent aerosol layers in the stratosphere
Extremely clean air on the ground, warm air intrusions and sulphate aerosol at high altitudes -- a research project has gained new insights into clouds in Antarctica.
Global warming's economic blow: Risks rise more rapidly for the rich
Researchers analyzed how erratic weather events, increasingly intensified by global warming, affect global production and consumption across different income groups.
Simple shift could make low Earth orbit satellites high capacity
Researchers have invented a technique that enables low Earth orbit satellite antennas to manage signals for multiple users at once, slashing costs and simplifying designs for communication satellites.
New method for fingerprint analysis holds great promise
Overlapping and weak fingerprints pose challenges in criminal cases. A new study offers a solution and brings hope for using chemical residues in fingerprints for personal profiling.
Folded or cut, this lithium-sulfur battery keeps going
Most rechargeable batteries that power portable devices, such as toys, handheld vacuums and e-bikes, use lithium-ion technology. But these batteries can have short lifetimes and may catch fire when damaged. To address stability and safety issues, researchers have designed a lithium-sulfur (Li-S) battery that features an improved iron sulfide cathode. One prototype remains highly stable over 300 charge-discharge cycles, and another provides power even after being folded or cut.
New discovery aims to improve the design of microelectronic devices
A new study is providing new insights into how next-generation electronics, including memory components in computers, breakdown or degrade over time.
Bacteria work together to thrive in difficult conditions
In a new study, researchers have determined through both statistical analysis and in experiments that soil pH is a driver of microbial community composition -- but that the need to address toxicity released during nitrogen cycling ultimately shapes the final microbial community.
Unveiling the math behind your calendar
In a world where organizing a simple meeting can feel like herding cats, new research reveals just how challenging finding a suitable meeting time becomes as the number of participants grows. The study dives into the mathematical complexities of this common task, offering new insights into why scheduling often feels so impossible.
Residents in San Joaquin Valley breathe chemical pesticides, according to new study
A new study found 22% of adults and 10% of children who participated in an air-quality study in California's San Joaquin Valley were breathing detectable levels of pesticides.
Ignore antifungal resistance in fungal disease at your peril, warn top scientists
Without immediate action, humanity will potentially face further escalation in resistance in fungal disease, a group of scientists from the around the world has warned. According to the scientists most fungal pathogens identified by the World Health Organization -- accounting for around 3.8 million deaths a year -- are either already resistant or rapidly acquiring resistance to antifungal drugs.
Breakthrough in proton barrier films using pore-free graphene oxide
Scientists have announced a groundbreaking development in hydrogen ion barrier films using graphene oxide (GO) that lacks internal pores. This innovative approach promises significant advancements in protective coatings for various applications.