
Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method
To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.
Rudmer Zwerver/shutterstock.com
Self-correcting quantum computers within reach?
Quantum computers promise to reach speeds and efficiencies impossible for even the fastest supercomputers of today. Yet the technology hasn't seen much scale-up and commercialization largely due to its inability to self-correct. Quantum computers, unlike classical ones, cannot correct errors by copying encoded data over and over. Scientists had to find another way. Now, a new paper in Nature illustrates a Harvard quantum computing platform's potential to solve the longstanding problem known as quantum error correction.
Traumatic memories can rewire the brain
Researchers found that fear conditioning led to learning-specific changes in neuronal-network activity in the dorsal part of the medial prefrontal cortex of mice. This study demonstrates the use of combined methods for detailed visualization of the dynamics of neural networks, and describes techniques that could be used to uncover additional information about the neurological changes associated with learning and memory.
Widely tuneable terahertz lasers boost photo-induced superconductivity in K3C60
Researchers have long been exploring the effect of using tailored laser drives to manipulate the properties of quantum materials away from equilibrium. One of the most striking demonstrations of these physics has been in unconventional superconductors, where signatures of enhanced electronic coherences and super-transport have been documented in the resulting non-equilibrium states. However, these phenomena have not yet been systematically studied or optimized, primarily due to the complexity of the experiments. Technological applications are therefore still far removed from reality. In a recent experiment, this same group of researchers discovered a far more efficient way to create a previously observed metastable, superconducting-like state in K3C60 using laser light.
Revolutionizing energy storage: Metal nanoclusters for stable lithium--sulfur batteries
Lithium–sulfur batteries (LSBs) offer a higher energy storage potential. However, issues like formation of lithium polysulfides and lithium dendrites lead to capacity loss and raise safety concerns. Now, researchers have developed a graphene separator embedded with platinum-doped gold nanoclusters, which enhance lithium-ion transport and facilitate redox reactions. This breakthrough addresses the long-standing issues associated with LSBs, setting the stage for their commercialization.
A better 'map' of the lights you see when you close your eyes can improve 'bionic eye' outcomes
Researchers have identified a new way of mapping ‘phosphenes’ – the visual perception of the bright flashes we see when no light is entering the eye – to improve the outcome of surgery for patients receiving a cortical visual prosthesis (‘bionic eye’).
Researchers developed a nanostructured light diffuser that provides balanced lighting by diffracting blue and red light, and can be cleaned by simple rinsing with water. The diffuser consists of cheap materials and can be shaped with common tools. A protective glass coating maintains the diffuser's optical performance yet adds durability. This work might improve the visual performance of everyday lighting displays.
Restoring nerve-muscle connections boosts strength of aging mice, study finds
A drug that boosts strength in injured or aging mice restores connections between nerves and muscle and suggests ways to combat weakness in humans due to aging, injury or disease.
Flooding that closed Alaska's Dalton Highway also caused widespread ground sinking
The massive 2015 flooding of the Sagavanirktok River in northern Alaska had immediate impacts, including closure of the Dalton Highway for several days, but it also contributed to longer-term ground subsidence in the permafrost-rich region.
New cyber algorithm shuts down malicious robotic attack
Researchers have designed an algorithm that can intercept a man-in-the-middle (MitM) cyberattack on an unmanned military robot and shut it down in seconds. The algorithm, tested in real time, achieved a 99% success rate.
New guidance issued on the determination of brain death
New guidance has been issued for clinicians on the determination of brain death, also known as death by neurologic criteria.
New study finds link between subjective and objective memory decline
Among people who report memory and thinking problems, some show no signs of a problem on standard tests, while others have subtle declines on their tests. A new study shows that people who have subtle problems with these tests may have an increased risk of developing mild cognitive impairment, which can be a precursor to dementia.
The good and bad uses of biomass for California
A new study examines the good and bad uses of biomass and the best pathways to meet California’s goal of reducing carbon dioxide emissions by 85% of 1990 levels by 2045.
NASA's Webb captures an ethereal view of NGC 346
One of the greatest strengths of NASA’s James Webb Space Telescope is its ability to give astronomers detailed views of areas where new stars are being born. The latest example, showcased here in a new image from Webb’s Mid-Infrared Instrument (MIRI), is NGC 346 – the brightest and largest star-forming region in the Small Magellanic Cloud.
Scientists discover 'flipping' layers in heterostructures to cause changes in their properties
Transition metal dichalcogenide (TMD) semiconductors are special materials that have long fascinated researchers with their unique properties. For one, they are flat, one-atom-thick two-dimensional (2D) materials similar to that of graphene. They are compounds that contain different combinations of the transition metal group (e.g., molybdenum, tungsten) and chalcogen elements (e.g., sulfur, selenium, tellurium).
By demonstrating that spaceflight doesn’t adversely affect the magnetism of moon rocks, researchers underscore the exciting potential of studying the magnetic histories stored in these samples.
Pleural mesothelioma: New therapeutic approach to enhance sensitivity to chemo- and radiotherapy
Pleural mesothelioma (PM) is mainly caused by asbestos exposure and characterized by poor prognosis and limited therapeutic options. A recent research study identified the oncoprotein YB-1 as an attractive therapeutic target in PM and demonstrates that indirect targeting of YB-1 is a promising approach to enhance sensitivity to chemo- and radiotherapy.
Exploring parameter shift for quantum fisher information
Scientists have developed a technique called 'Time-dependent Stochastic Parameter Shift' in the realm of quantum computing and quantum machine learning. This breakthrough method revolutionizes the estimation of gradients or derivatives of functions, a crucial step in many computational tasks.
Tens of thousands of endangered sharks and rays caught off Congo
Tens of thousands of endangered sharks and rays are caught by small-scale fisheries off the Republic of the Congo each year, new research shows.
It is now apparent that the mass-produced artefacts of technology in our increasingly densely populated world – whether electronic devices, cars, batteries, phones, household appliances, or industrial robots – are increasingly at odds with the sustainable bounded ecosystems achieved by living organisms based on cells over millions of years. Cells provide organisms with soft and sustainable environmental interactions with complete recycling of material components, except in a few notable cases like the creation of oxygen in the atmosphere, and of the fossil fuel reserves of oil and coal (as a result of missing biocatalysts). However, the fantastic information content of biological cells (gigabits of information in DNA alone) and the complexities of protein biochemistry for metabolism seem to place a cellular approach well beyond the current capabilities of technology, and prevent the development of intrinsically sustainable technology.
The prevalence of malaria infections varies among migrant populations
The prevalence of malaria infections among migrants from sub-Saharan Africa is considerably high (8%), while Asian and Latin American migrants have a much lower prevalence, according to a new study.
Rivers may not recover from drought for years
Lack of rainfall is not the only measure of drought. New research shows that despite a series of storms, the impact of drought can persist in streams and rivers for up to 3.5 years.
Jet lag disorder associated with shift work can lead to brain changes increasing appetite
Scientists have uncovered why night shift work is associated with changes in appetite in a new study. The findings could help the millions of people that work through the night and struggle with weight gain.
Killer whales' diet more important than location for pollutant exposure
Both elegant and fierce, killer whales are some of the oceans’ top predators, but even they can be exposed to environmental pollution. Now, in the largest study to date on North Atlantic killer whales, researchers report the levels of legacy and emerging pollutants in 162 individuals’ blubber. The animals’ diet, rather than location, greatly impacted contaminant levels and potential health risks — information that’s helpful to conservation efforts.
Metal-organic frameworks could someday deliver antibacterial nitric oxide
Because metal-organic frameworks (MOFs) — highly porous metal complexes — are so structurally and chemically diverse, they could be used for many applications, such as drug delivery and environmental clean-up. But researchers still need to get a better understanding of how they function, especially when embedded in polymers. Researchers have now developed and characterized nitric oxide (NO)-storing MOFs embedded in a thin film with novel antibacterial potential.
'Ultrashort' PFAS compounds detected in people and their homes, study shows
Per- and polyfluoroalkyl substances (PFAS) have become ubiquitous throughout the environment, and increasing evidence has demonstrated their deleterious effects. A group of smaller, fluorinated compounds are becoming replacements for these 'forever chemicals,' though research suggests the smaller versions could also be harmful. Now, a study reports that the levels of these substances in many indoor and human samples are similar to or higher than those of legacy PFAS.
Not lazy at all: Honey bee drones
Sometimes it is worthwhile to look at the details, to study aspects that seem to be uninteresting or were previously ignored, and see noteworthy phenomena come to light. Researchers showed that male honey bees (drones), long considered lazy, are (at times) the most active members of the colony.
Omega-3 discovery moves us closer to 'precision nutrition' for better health
Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.
A step towards AI-based precision medicine
Artificial intelligence, AI, which finds patterns in complex biological data could eventually contribute to the development of individually tailored healthcare. Researchers have developed an AI-based method applicable to various medical and biological issues. Their models can for instance accurately estimate people's chronological age and determine whether they have been smokers or not.
Remains of artificial turf is an important source of pollution of the aquatic environment
Every year, around 1,200 and 1,400 artificial turf sports fields are installed in the European Union. These fields are made up of synthetic fibers, mainly plastics, that mimic the appearance of natural grass. Recently, scientists conducted a study that characterizes and quantifies the presence of artificial turf fibers in samples collected from surface waters of the Catalan coast and the Guadalquivir River. The findings indicate that artificial turfs can be an important source of pollution in the aquatic environment, accounting for up to 15% of the plastics larger than 5 mm in length that are found floating in the aquatic environment.
Plastic use in agriculture must be reduced, according to new research
Plastic use in agriculture must be reduced in order to mitigate pollution and prevent toxic chemicals from leaching into the soil and adversely affecting human health, according to a new study.
Using different flours for sourdough fosters different bacteria -- and flavors
A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.
Study clearly identifies nutrients as a driver of the Great Atlantic Sargassum Belt
Under normal conditions, the floating macroalgae Sargassum spp. provide habitat for hundreds of types of organisms. However, the Great Atlantic Sargassum Belt (GASB) that emerged in 2011 has since then caused unprecedented inundations of this brown seaweed on Caribbean coastlines, with harmful effects on ecosystems while posing challenges to regional economies and tourism, and concerns for respiratory and other human health issues.
Practicing mindfulness with an app may improve children's mental health
Researchers report children who used a mindfulness app at home for 40 days showed improvements in several aspects of mental health, including reductions in stress and negative emotions such as loneliness and fear.
New easy-to-use optical chip can self-configure to perform various functions
Researchers have developed an easy-to-use optical chip that can configure itself to achieve various functions. The positive real-valued matrix computation they have achieved gives the chip the potential to be used in applications requiring optical neural networks.
Warm summers and wet winters yield better wine vintages
Wine quality is notorious for varying from year to year, but what makes for a 'good year?' Researchers show that weather plays an important role in determining wine quality. By analyzing 50 years’ worth of wine critic scores from the Bordeaux wine region in relation to that year’s weather, the researchers showed that higher quality wine is made in years with warmer temperatures, higher winter rainfall, and earlier, shorter growing seasons—conditions that climate change is predicted to make more frequent.
Researchers capture first-ever afterglow of huge planetary collision in outer space
A chance social media post by an eagle-eyed amateur astronomer sparked the discovery of an explosive collision between two giant planets, which crashed into each other in a distant space system 1,800 light years away from planet Earth.
Certain navigational mistakes could be early signs of Alzheimer's disease
People with early Alzheimer’s disease have difficulty turning when walking, according to a new study using virtual reality.
An AI tool that can help forecast viral outbreaks
EVEscape predicts future viral mutations, new variants using evolutionary, biological information.
Fruit fly serenade: Neuroscientists decode their tiny mating song
An extremely supportive atmosphere for new ideas laid the foundation for an 'Aha moment' about a toggle-switch in the fruit fly brain. Do humans have one, too?
Doubling down on known protein families
A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'
AI speeds up identification brain tumor type
What type of brain tumor does this patient have? AI technology helps to determine this as early as during surgery, within 1.5 hours. This process normally takes a week. The new technology allows neurosurgeons to adjust their surgical strategies on the spot.
A new way to erase quantum computer errors
Researchers have demonstrated a type of quantum eraser. The physicists show that they can pinpoint and correct for mistakes in quantum computing systems known as 'erasure' errors.
'Mona Lisa' hides a surprising mix of toxic pigments, study shows
Leonardo da Vinci is renowned to this day for innovations in fields across the arts and sciences. Now, new analyses show that his taste for experimentation extended even to the base layers underneath his paintings. Surprisingly, samples from both the 'Mona Lisa' and the 'Last Supper' suggest that he experimented with lead(II) oxide, causing a rare compound called plumbonacrite to form below his artworks.
Drug-filled nanocapsule helps make immunotherapy more effective in mice
Researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.
'Starquakes' could explain mystery signals
Fast radio bursts, or FRBs, are an astronomical mystery, with their exact cause and origins still unconfirmed. These intense bursts of radio energy are invisible to the human eye, but show up brightly on radio telescopes. Previous studies have noted broad similarities between the energy distribution of repeat FRBs, and that of earthquakes and solar flares. However, new research has looked at the time and energy of FRBs and found distinct differences between FRBs and solar flares, but several notable similarities between FRBs and earthquakes. This supports the theory that FRBs are caused by 'starquakes' on the surface of neutron stars. This discovery could help us better understand earthquakes, the behavior of high-density matter and aspects of nuclear physics.
Epiphytes, amazing plants like moss and bromeliads found in trees, face growing threats
Epiphytes, plants such as orchids and mosses that grow in trees, draw nutrients from the air and create refuge for all sorts of other life forms. They are the foundation of forest canopy ecosystems, but they are facing threats from human and natural disturbances.
Researchers reconstruct speech from brain activity, illuminates complex neural processes
Researchers created and used complex neural networks to recreate speech from brain recordings, and then used that recreation to analyze the processes that drive human speech.
Study shows testimonials can open acceptance to differing opinions on controversial topics
Researchers led a study in which they surveyed people on their views about a controversial topic, in this case, physician-assisted suicide. Participants then randomly red either a personal testimonial or informative article on the topic, also randomly assigned as either pro or con regarding the issue. Those who read a testimonial opposed to their original viewpoint showed to be the most open to considering the views of those different than theirs in post surveys. The results shows testimonials featuring peoples' lived-experience can be an effective way for communicators to reach people on controversial, yet important topics, and can be effective for those without large communications budgets.
Experiencing record-breaking heat days affects perception of weather trends
Research finds that experiencing days in which the temperature exceeds previous highs for that time of year affects people’s perception of weather trends.
Death is only the beginning: Birds disperse eaten insects' eggs
Relationship patterns among flightless stick insects suggest that birds disperse the eggs after eating gravid females. Lab experiments previously suggested the possibility, but a new genetic analysis of natural populations in Japan now supports the idea.