New tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious RSV LRTI, according to new research.
Alaska's rusting waters: Pristine rivers and streams turning orange
Dozens of Alaska's rivers and streams are turning orange. The staining could be the result of minerals exposed by thawing permafrost and climate change, finds a new study.
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Scientists create tailored drug for aggressive breast cancer
Scientists have used breast cancer cells' weakness against themselves by linking a tumor-selective antibody with a cell-killing drug to destroy hard-to-treat tumors.
Drug-like inhibitor shows promise in preventing flu
Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.
Cosmic rays illuminate the past
Researchers have for the first time been able to pin down a prehistoric settlement of early farmers in northern Greece dating back more than 7,000 years to the year. For this they combined annual growth ring measurements on wooden building elements with the sudden spike of cosmogenic radiocarbon in 5259 BC. This provides a reliable chronological reference point for many other archaeological sites in Southeast Europe.
PFAS exposure in men linked to the health of their offspring
Researchers are reporting new findings that demonstrate a link between exposure to per- and polyfluorinated alkyl substances (PFAS) in males and health issues in their offspring.
Ruptured Achilles tendon shows faster repair amid plasma irradiation treatment
Researchers have been focusing on non-thermal atmospheric-pressure plasma as a treatment method that can shorten recovery times, such as for tendon repair. Using a helium plasma jet, they demonstrated that irradiation of ruptured Achilles tendons showed accelerated regeneration and increased strength at an earlier stage than if the injury site was not irradiated.
Complete Stellar Collapse: Unusual star system proves that stars can die quietly
University of Copenhagen astrophysicists help explain a mysterious phenomenon, whereby stars suddenly vanish from the night sky. Their study of an unusual binary star system has resulted in convincing evidence that massive stars can completely collapse and become black holes without a supernova explosion.
How plants 'mate' for life and repel other suitors
Researchers have used a unique microscopic technique to examine the dynamics of pollen tubes in the Arabidopsis plant. They were able to observe the mechanism of one-to-one pollen tube guidance, a process that ensures successful pollination of plants. This process is influenced by multi-step repelling and attracting signals. The results are important for the cultivation of crops, especially under unfavorable environmental conditions.
Chocolate that harnesses the full potential of the cocoa fruit
Researchers have developed a type of chocolate that is more sustainable and nutritious than conventional varieties. Cocoa-fruit chocolate uses cocoa fruit jelly as a replacement for powdered sugar, reducing the sugar content and increasing the product's nutritional value. This new chocolate recipe also has the potential to diversify the income sources of small farmers.
Night-time heat significantly increases the risk of stroke
Researchers show that nocturnal heat significantly increases the risk of stroke. The findings can contribute to the development of preventive measures: With them, the population can better protect themselves against the risks of climate change with increasingly frequent hot nights. In addition, knowledge of the consequences of hot nights can improve patient care.
Researchers introduce programmable materials to help heal broken bones
Natural materials like bone, bird feathers and wood have an intelligent approach to physical stress distribution, despite their irregular architectures. However, the relationship between stress modulation and their structures has remained elusive. A new study that integrates machine learning, optimization, 3D printing and stress experiments allowed engineers to gain insight into these natural wonders by developing a material that replicates the functionalities of human bone for orthopedic femur restoration.
Rabies outbreaks in Costa Rica cattle linked to deforestation
Deforestation in Costa Rica raises the risk of cattle becoming infected with rabies by vampire bats, finds a new study.
New therapeutic avenues in bone repair
Researchers have shown that a naturally occurring peptide (small protein) holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs.
Researchers discover hidden step in dinosaur feather evolution
Scientists discover 'zoned development' in dinosaur skin, with zones of reptile-style scales and zones of bird-like skin with feathers. A new dinosaur skin fossil has been found to be composed of silica -- the same as glass.
Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans
Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.
A new gene-editing system tackles complex diseases
Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing -- installing multiple point mutations simultaneously across the genome. Researchers have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.
Clarifying the cellular mechanisms underlying periodontitis with an improved animal model
Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.
Drug helps reprogram macrophage immune cells, suppress prostate and bladder tumor growth
A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to new research.
Green infrastructure plans need to consider historical racial inequalities
Urban greening projects should consider historical development patterns and past discriminatory practices to avoid exacerbating the unequal distribution of environmental benefits, says an urban and regional planning professor.
Highly sensitive fiber optic gyroscope senses rotational ground motion around active volcano
Researchers have built a prototype fiber optic gyroscope for high resolution, real-time monitoring of ground rotations caused by earthquakes in the active volcanic area of Campi Flegrei in Naples, Italy. A better understanding of the seismic activity in this highly populated area could improve risk assessment and might lead to improved early warning systems.
Warming climate intensifies flash droughts worldwide
Sudden, severe dry spells known as flash droughts are rising in intensity around the world, with a notable exception in mountainous Central Asia, where flash drought extent is shrinking, according to new research. Heat and changes to precipitation patterns caused by a warming climate are driving these trends, the study found.
A rise in sea urchins and related damage to kelp forests impacts Oregon's gray whales and their food
A recent boom in the purple sea urchin population off the southern Oregon Coast appears to have had an indirect and negative impact on the gray whales that usually forage in the region, a new study shows.
New research on a field of pockmarks -- large, circular depressions on the seafloor -- offshore of Central California has revealed that powerful sediment flows, not methane gas eruptions, maintain these prehistoric formations.
An increase in nightmares and hallucinations -- or 'daymares' -- could herald the onset of autoimmune diseases such as lupus.
Electric school buses may yield significant health and climate benefits, cost savings
Replacing diesel school buses with electric school buses may yield up to $247,600 in climate and health benefits per individual bus, according to a new study. The researchers found that these benefits -- including fewer greenhouse gas emissions and reduced rates of adult mortality and childhood asthma -- and their associated savings are strongest in large cities and among fleets of old (2005 and before) buses.
Yoga and meditation-induced altered states of consciousness are common in the general population
A new study finds that altered states of consciousness associated with yoga, meditation, mindfulness, and other practices are common, and mostly positive or even transformative, but that for some people, they can be linked to suffering.