Better medical record-keeping needed to fight antibiotic overuse
A lack of detailed record-keeping in clinics and emergency departments may be getting in the way of reducing the inappropriate use of antibiotics, a pair of new studies suggests. In one of the studies, about 10% of children and 35% of adults who got an antibiotic prescription during an office visit had no specific reason for the antibiotic in their record.
The latest findings forecast that global life expectancy will increase by 4.9 years in males and 4.2 years in females between 2022 and 2050. Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of increased life expectancy across geographies. The trend is largely driven by public health measures that have prevented and improved survival rates from cardiovascular diseases, COVID-19, and a range of communicable, maternal, neonatal, and nutritional diseases (CMNNs).
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Modern plant enzyme partners with surprisingly ancient protein
Scientists have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected. This new research explored the origin and evolution of the biochemical machinery that builds lignin, a structural component of plant cell walls with significant impacts on the clean energy industry.
A recombinant form of human ADAMTS13 approved for a different condition helped to save the life of a young mother with immune thrombotic thrombocytopenic purpura.
Physicists propose path to faster, more flexible robots
Physicists revealed a microscopic phenomenon that could greatly improve the performance of soft devices, such as agile flexible robots or microscopic capsules for drug delivery.
Sweet taste receptor affects how glucose is handled metabolically by humans
The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption and assimilation, as part of this system. A team found that stimulation and inhibition of the sweet receptor helps regulate glucose metabolism in humans and may have implications for managing such metabolic disorders as diabetes.
How heatwaves are affecting Arctic phytoplankton
The basis of the marine food web in the Arctic, the phytoplankton, responds to heatwaves much differently than to constantly elevated temperatures. This has been found by the first targeted experiments on the topic. The phytoplankton's behavior primarily depends on the cooling phases after or between heatwaves.
Differing values of nature can still lead to joined up goals for sustainability
Recognizing and respecting the different ways nature is valued can enable better environmental decision-making, according to new research.
A new commentary paper puts forth a transformative solution to the unsustainable reliance on fossil resources by the chemical industry: catalysis to leverage sustainable waste resources, ushering the industry from a linear to a circular economy.
Diamond glitter: A play of colors with artificial DNA crystals
Using DNA origami, researchers have built a diamond lattice with a periodicity of hundreds of nanometers -- a new approach for manufacturing semiconductors for visible light.
Zombie cells in the sea: Viruses keep the most common marine bacteria in check
Marine microbes control the flux of matter and energy essential for life in the oceans. Among them, the bacterial group SAR11 accounts for about a third of all the bacteria found in surface ocean waters. A study now reveals that at times nearly 20% of SAR11 cells are infected by viruses, significantly reducing total cell numbers. The viruses can also transform these once thriving bacteria into zombies, a phenomenon observed for the first time and widespread in the oceans.
Plants restrict use of 'Tipp-Ex proteins'
Plants have special corrective molecules at their disposal that can make retrospective modifications to copies of genes. However, it would appear that these 'Tipp-Ex proteins' do not have permission to work in all areas of the cell, only being used in chloroplasts and mitochondria. A study has now explained why this is the case. It suggests that the correction mechanism would otherwise modify copies that have nothing wrong with them, with fatal consequences for the cell.
Seeing not just with the eyes: Degree of arousal affects perception
The brain modulates visual signals according to internal states, as a new study by neuroscientists reveals.
Fruit fly wing research offers window into birth defects
If fruit fly wings do not develop into the right shape, the flies will die. Researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.
Ancient arachnid from coal forests of America stands out for its spiny legs
The spiny legged 308-million-year-old arachnid Douglassarachne acanthopoda was discovered the famous Mazon Creek locality.
Anti-diabetic treatment associated with reduced risk of developing blood cancer
People who use metformin are less likely to develop a myeloproliferative neoplasm (MPN) over time, indicating that the treatment may help prevent the development of certain types of cancers, according to a new study.
A trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
A powerful tool speeds success in achieving highly efficient thermoelectric materials
Thermoelectric materials could play an important role in the clean energy transition, as they can produce electricity from sources of heat that would otherwise go to waste. Researchers report a new approach to efficiently predict when thermoelectric materials will have improved performance in converting heat into electricity.
Airborne technology brings new hope to map shallow aquifers in Earth's most arid deserts
The new technique will map the top of the aquifer, called the 'water table,' spanning areas as large as hundreds of kilometers using a radar mounted on a high-altitude aircraft. According to the researchers, Desert-SEA will measure the variabilities in the depth of the water table on a large scale, allowing water scientists to assess the sustainability of these aquifers without the limitations associated with in-situ mapping in harsh and inaccessible environments.
Large language model-based chatbots can't effectively recognize users' motivation when they are hesitant about making healthy behavior changes, but they can support those who are committed to take action, say researchers.
Normothermic perfusion system extends life of organs waiting for transplant
In the United States, about 30-40% of donor hearts aren't considered for transplant due to inadequate function in the donor. This leads to a drop in the number of donated hearts that are available to be matched with someone who needs a heart transplant.
High-frequency electrical 'noise' may result in congenital night blindness
In what they believe is a solution to a 30-year biological mystery, neuroscientists say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.
Imaging fibrous structure abnormalities of the white of the eye in myopathic patients
Abnormalities in the shape of the sclera, the white of the eye, can cause various complications and lead to blindness. However, techniques to observe the sclera in detail, such as its fibrous structure, are lacking. Now, researchers have used polarization-sensitive optical computed tomography to accurately visualize the density and orientation of scleral fibers in the eyes of living patients, opening doors to understanding ocular pathologies better and developing effective diagnostic and therapeutic strategies.
Important brain structures that are key for signaling in the brain are narrower and less dense in females, and more likely to be damaged by brain injuries, such as concussion. Long-term cognitive deficits occur when the signals between brain structures weaken due to the injury. The structural differences in male and female brains might explain why females are more prone to concussions and experience longer recovery from the injury than their male counterparts.
Scientists use generative AI to answer complex questions in physics
Researchers used generative AI to develop a physics-informed technique to classify phase transitions in materials or physical systems that is much more efficient than existing machine-learning approaches.
New sensor gives unprecedented look at changes in cell's energy 'currency'
A new sensor is giving researchers the best look yet at ATP levels inside living cells, enabling scientists to study in greater detail than ever before how fluctuations in this cellular currency affect the cell and contribute to disease.
The vicious cycle of protein clumping in Alzheimer's disease and normal aging
To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health.