Are you curious? It might help you stay sharp as you age
Psychology literature has shown that curiosity tends to decline with age. Psychologists shows one type of curiosity can increase well into old age, contradicting prior research. Older adults who maintain curiosity and want to learn new things relevant to their interests may be able to offset or even prevent Alzheimer's disease. Conversely, those who show muted curiosity and disinterest may be at risk for dementia.
Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior.
Insights on preventing organ transplant rejection
Researchers identified a natural 'brake' within the innate immune system: the inhibitory receptor Siglec-E (SigE) and its human counterparts, Siglec-7 and Siglec-9. This receptor helps prevent overactivation of immune cells that drive rejection. When this brake is missing, inflammation worsens, leading to faster rejection in preclinical models. Importantly, transplant patients with higher levels of Siglec-7 and Siglec-9 showed better graft survival, highlighting this pathway as a promising target for new therapies.
Biologists create a one-stop shop for world's most charismatic plants, ferns
Biologists have create a web portal for the world's most charismatic plants, ferns.
Dual-action approach targeting inflammation shows potential as Type 1 diabetes treatment
A new strategy may help prevent or slow the progression of Type 1 diabetes.
Warming climate making fine particulate matter from wildfires more deadly and expensive
Scientists say human-caused climate change led to 15,000 additional early deaths from wildfire air pollution in the continental United States during the 15-year period ending in 2020.
Feat of 'dung-gineering' turns cow manure into one of world's most used materials
A new technique to extract tiny cellulose strands from cow dung and turn them into manufacturing-grade cellulose, currently used to make everything from surgical masks to food packaging, has been developed.
A pipette that can activate individual neurons
Researchers have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu. Controlling the concentration of different ions can provide important insights into how individual brain cells are affected, and how cells work together. The pipette could also be used for treatments.
Transforming hospital sanitation: Autonomous robots for wiping and UV-C disinfection
A research team develops disinfection robot combining physical wiping and UV-C sterilization.
Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction
Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction A portable device that instantly detects illicit street drugs at very low concentrations, thereby highlighting the risks they pose. The device has the potential to address the growing global problem of people unknowingly taking drugs that have been mixed with undeclared substances, including synthetic opioids such as fentanyl and nitazenes.
Viruses under the super microscope: How influenza viruses communicate with cells
Influenza viruses are among the most likely triggers of future pandemics. A research team has developed a method that can be used to study the interaction of viruses with host cells in unprecedented detail. With the help of their new development, they have also analyzed how novel influenza viruses use alternative receptors to enter target cells.
New algorithms can help GPs predict which of their patients have undiagnosed cancer
Two new advanced predictive algorithms use information about a person's health conditions and simple blood tests to accurately predict a patient's chances of having a currently undiagnosed cancer, including hard to diagnose liver and oral cancers. The new models could revolutionize how cancer is detected in primary care, and make it easier for patients to get treatment at much earlier stages.
The world's wealthiest 10% caused two thirds of global warming since 1990
Wealthy individuals have a higher carbon footprint. A new study quantifies the climate outcomes of these inequalities. It finds that the world's wealthiest 10% are responsible for two thirds of observed global warming since 1990 and the resulting increases in climate extremes such as heatwaves and droughts.
New study tracks air pollution and CO2 emissions across thousands of cities worldwide
In a sweeping new study of more than 13,000 urban areas worldwide, researchers have mapped air pollution levels and carbon dioxide emissions, providing comprehensive global analysis of urban environmental quality.
A 'roadmap' of the fruit fly brain
Researchers have gained comprehensive insights into the entire nervous system of the fruit fly (Drosophila melanogaster). The study describes in detail the neurons that span the entire nervous system of the adult fruit fly. The researchers also compared the complete set of neural connections (the connectome) in a female and a male specimen -- and identified differences.
Across the globe, monsoon rainfall switches on in spring and off in autumn. Until now, this seasonal pattern was primarily understood as an immediate response to changes in solar radiation. A new study shows that the atmosphere can store moisture over extended periods, creating a physical memory effect. It allows monsoon systems to flip between two stable states. Disrupting this delicate balance, would have severe consequences for billions of people in India, Indonesia, Brazil and China.
Losing a parent may increase children's risk of being bullied
A new study surveyed 21,000 children in China and found that the association between parental bereavement and school bullying varied by sex of the child and deceased parent, age when the death occurred, and geographical area. Adolescents in rural areas, girls, and older youth (ages 13-17) were at higher risk of bullying after either parent died.
Is virtual-only couture the new clothing craze?
As fast fashion continues to fill wardrobes and landfills at a staggering pace, new research suggests that the future of fashion might lie not in fabric, but in pixels.
Scientists discover the genes that influence when babies start walking
The age at which babies take their first steps is strongly influenced by their genes, according to new research. Scientists analyzed the genetic information of more than 70,000 infants. They identified 11 genetic markers influencing when babies start walking, thus offering multiple targets for future in-depth biological investigation.
Knowing your Alzheimer's risk may ease anxiety but reduce motivation for healthy habits
Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high risk, according to a new study.
Klotho: A protein that promotes healthy aging and improves longevity
An international study has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health when aging.
New research has shown how small, inexpensive drones combined with free, open source software can be used by community forest organizations to calculate and monitor the amount of carbon stored in their forests.
Specialized face mask can detect kidney disease with just your breath
Surgical face masks help prevent the spread of airborne pathogens and therefore were ubiquitous during the COVID-19 pandemic. Now, a modified mask could also protect a wearer by detecting health conditions, including chronic kidney disease. Researchers incorporated a specialized breath sensor within the fabric of a face mask to detect metabolites associated with the disease. In initial tests, the sensor correctly identified people with the condition most of the time.
Stellar collapse and explosions distribute gold throughout the universe
Magnetar flares, colossal cosmic explosions, may be directly responsible for the creation and distribution of heavy elements across the universe, suggests a new study.
Fewer parasites in the Indian River lagoon signal big ecosystem problems
Parasites are crucial indicators of ecosystem health, and their absence can signal trouble. Once pristine, Florida's Indian River Lagoon (IRL) now faces pollution and algal blooms that have damaged essential habitats like seagrass beds. New research finds parasite levels in the IRL are significantly lower than in comparable ecosystems worldwide -- 11% lower overall and 17% lower for larval parasites requiring multiple hosts. This sharp decline suggests a disrupted food web likely caused by pollution and habitat degradation, and a less resilient and more vulnerable ecosystem.
Risk groups for type 2 diabetes can also be identified at an older age
A recent study found that six cardiometabolic risk groups previously identified in middle-aged individuals can also be applied to older adults without diabetes. Using data from the KORA F4/FF4 study of people aged 61 to 82, researchers identified clusters with varying risks of developing type 2 diabetes and related complications. One cluster, marked by high inflammatory load and insulin-resistant fatty liver, showed particularly high risk. The study highlights the importance of personalized risk assessment and early prevention strategies even in older age.
New roadmap advances catalytic solutions to destroy 'forever chemicals'
Researchers have outlined a bold new roadmap for harnessing heterogeneous catalysis to destroy per- and polyfluoroalkyl substances (PFAS), the so-called 'forever chemicals' that have contaminated water supplies worldwide.
Junk food for thought: Landmark study directly links ultra-processed foods to poor health
A landmark study exploring consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes.
AI-human task-sharing could cut mammography screening costs by up to 30%
The most effective way to harness the power of artificial intelligence when screening for breast cancer may be through collaboration with human radiologists -- not by wholesale replacing them, says new research.
NFL players more likely to injure knee after shorter rest period
National Football League (NFL) players may be more likely to sustain a specific type of knee injury if they have a shorter period of rest between games.
Physicists snap the first images of 'free-range' atoms
Physicists captured the first images of individual atoms freely interacting in space. The pictures reveal correlations among the 'free-range' particles that until now were predicted but never directly observed.
Triassic fossil reveals nature's best jaw for hunting fast fish
Newly discovered species of extinct fish shows striking similarities to unrelated modern-day predators, suggesting certain traits have emerged multiple times and remained consistent over hundreds of millions of years.
Smart lactation pads can monitor safety of breast milk in real time
Scientists have developed a lactation pad equipped with sensing technology that allows parents of newborns to monitor breast milk in real time. The device is capable of ensuring that breast milk contains safe levels of the painkiller acetaminophen, which is often prescribed after childbirth and can be transferred to breastfeeding infants.
Piecing together the brain puzzle
Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this complicated network requires a precise look into how these nerve cells are arranged and connected. A new method makes use of off-the-shelf light microscopes, hydrogel and deep learning.
Birds form bonds that look a lot like friendship
A study of starlings in Africa shows that they form long-term social bonds similar to human friendships.
Comb jellies reveal ancient origins of animal genome regulation
Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but usually over short distances across the DNA sequence, with the on/off switch typically right next to a gene. This basic form of genomic regulation is probably as old as life on Earth. A new study finds that the ability to control genes from far away, over many tens of thousands of DNA letters, evolved between 650 and 700 million years ago. It probably appeared at the very dawn of animal evolution, around 150 million years earlier than previously thought. The critical innovation likely originated in a sea creature, the common ancestor or all extant animals.
Climate change: Future of today's young people
Climate scientists reveal that millions of today's young people will live through unprecedented lifetime exposure to heatwaves, crop failures, river floods, droughts, wildfires and tropical storms under current climate policies. If global temperatures rise by 3.5 C by 2100, 92% of children born in 2020 will experience unprecedented heatwave exposure over their lifetime, affecting 111 million children. Meeting the Paris Agreement's 1.5 C target could protect 49 million children from this risk. This is only for one birth year; when instead taking into account all children who are between 5 and 18 years old today, this adds up to 1.5 billion children affected under a 3.5 C scenario, and with 654 million children that can be protected by remaining under the 1.5 C threshold.
Teens driving older vehicles have increased risk for fatal crashes
Researchers reviewed US national fatal crash data (2016-2021) and examined the vehicle age and driver assistance technologies of vehicles driven by teen and middle-aged drivers, and their associations with driver deaths during fatal crashes.
AI model improves delirium prediction, leading to better health outcomes for hospitalized patients
An artificial intelligence (AI) model improved outcomes in hospitalized patients by quadrupling the rate of detection and treatment of delirium. The model identifies patients at high risk for delirium and alerts a specially-trained team to assess the patient and create a treatment plan, if needed.
Childhood brain tumors develop early in highly specialized nerve cells
Medulloblastomas, brain tumors in children, are thought to develop between the first trimester of pregnancy and the end of the first year of life. Researchers have now analyzed the genetic changes of each individual cancer cell in tumor samples in order to reconstruct which genetic changes occur first during tumor development and when.
A new class of molecules against cancer cells refractory to standard treatments
A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight against metastatic cancer is based on identifying the cellular site for ferroptosis initiation, a natural process, catalyzed by iron, that sparks the oxidative degradation of cell membranes.
Neuroscientists pinpoint where (and how) brain circuits are reshaped as we learn new movements
Brain researchers have identified a bridge between the thalamus and the cortex as the key area that is modified during motor learning functions. They found that such learning does much more than adjust activity levels, it sculpts the circuit's wiring, refining the conversation between brain regions.
Scientists map tongue's sweet sensor, may lead to new ways to curb sugar cravings
Scientists have mapped the 3-D structure of the human sweet taste receptor, the molecular machine that allows us to taste sweet things. This could lead to the discovery of new regulators of the receptor that would significantly alter our attraction to and appetite for sugar.
A culturally adapted obesity prevention for Latino families
A research team has adapted an intervention for childhood obesity prevention to better serve Latina mothers, non-maternal caregivers, and families of low-income backgrounds in Inland Southern California. The study could make significant contributions to public health by ensuring that early childhood obesity prevention strategies begin in infancy with infant feeding and are culturally and linguistically relevant for immigrant communities.
Researchers restore antibiotic effect in the event of resistance
Bacterial resistance negates the effect of antibiotics in the treatment of infection. Using mouse models, researchers now show that if antibiotics are administered with an enzyme called endolysin, the combined effect protects against infection by resistant bacteria in all bodily organs -- including the brain, which antibiotics alone have difficulty reaching.
New vacuum-assisted extrusion technique improves performance of polymer prints
Scientists have developed a vacuum-assisted extrusion method that reduces internal porosity -- by up to 75% -- in large-scale 3D-printed polymer parts. Large-scale additive manufacturing has been hindered by internal porosity that weaken printed components. Reducing porosity is key to improving overall performance. Researchers tackled this challenge with a novel approach: integrating a vacuum hopper during the extrusion process to remove trapped gases and minimize void formation in fiber-reinforced materials.
Cracking the code: Deciphering how concrete can heal itself
Lichen is an understated presence in our everyday world, often found clinging to trees and rocks. Its true beauty lies in its unique symbiotic system of fungi and algae, or cyanobacteria, that form a self-sustaining partnership, allowing it to thrive in even the harshest conditions. With that inspiration, researchers created a synthetic lichen system that collaborates like natural lichens. Their system uses cyanobacteria, which turns air and sunlight into food, and filamentous fungi, which produces minerals that seal the cracks. Working together, these microbes survive on nothing more than air, light and water. The autonomy of this system sets it apart from previous self-healing concrete endeavors.
Eating a healthy diet as a child is linked to girls having their first menstrual period at an older age than those who consumed a less healthy diet, according to a new study. The findings remained unaltered by the girls' body mass index or height, both of which have been associated with the earlier onset of periods. The study has implications for health in later life as it is well known that women who started their periods at an early age may be at higher risk for diabetes, obesity, breast cancer and diseases of the heart and blood vessels.
More social parrots have a better vocabulary
For social animals, communication is a key that unlocks the benefits of group living. It's well known that animals with more complex social lives tend to have more intricate ways of communicating, from the clicks and whistles of dolphins to the calls of primates. While this pattern is found broadly in many species, a new study on wild parrots drills deep into the social and vocal lives of individual birds. Researchers analyzing the social networks of monk parakeets in Spain have uncovered how an individual's social ties shapes the calls these birds make.
T. rex's direct ancestor crossed from Asia to North America
Tyrannosaurus rex evolved in North America, but its direct ancestor came from Asia, crossing a land bridge connecting the continents more than 70 million years ago, according to a new study.
Vapor-deposited perovskite semiconductors power next generation circuits
A research team has developed a groundbreaking technology poised to revolutionize next-generation displays and electronic devices.
Replanted rainforests may benefit from termite transplants
Termites -- infamous for their ability to destroy wood -- are rarely welcomed into rainforests that have been painstakingly replanted. But a new paper suggests that termite transplants may be necessary to help regenerating forests to thrive. Scientists found that termites are not thriving in replanted rainforests in Australia. Because decomposers like termites are essential for recycling nutrients and carbon, the researchers worry that the insect's slow recovery could hinder the growth and health of the young forests.