Computer scientists unveil novel attacks on cybersecurity
Researchers have found two novel types of attacks that target the conditional branch predictor found in high-end Intel processors, which could be exploited to compromise billions of processors currently in use.
Using stem cell-derived heart muscle cells to advance heart regenerative therapy
Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In a recent study, researchers tested a novel approach that involves injecting 'cardiac spheroids,' cultured from human stem cells, directly into damaged ventricles. The highly positive outcomes observed in primate models highlight the potential of this strategy.
Advance in the treatment of acute heart failure identified
A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
Early trauma cuts life short for squirrels, and climate change could make matters worse
Life can be tough for young red squirrels living in the Canada's Yukon territory, where frigid winters, food scarcity and predators threaten their long-term survival. Scientists want to know what factors might protect young squirrels, especially as their environment becomes more impacted by climate change.
Image: red squirrel, Nikolay Zaborskikh/Shutterstock.com
A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.
Climate change could become the main driver of biodiversity decline by mid-century
Global biodiversity has declined between 2% and 11% during the 20th century due to land-use change alone, according to a large multi-model study. Projections show climate change could become the main driver of biodiversity decline by the mid-21st century.
Vitamin D alters mouse gut bacteria to give better cancer immunity
Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.
Food in sight? The liver is ready!
What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Voluntary corporate emissions targets not enough to create real climate action
Companies' emissions reduction targets should not be the sole measure of corporate climate ambition, according to a new perspective paper.
Curiosity promotes biodiversity
Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Airborne single-photon lidar system achieves high-resolution 3D imaging
Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D images with a low-power laser. This advance could make single-photon lidar practical for air and space applications such as environmental monitoring, 3D terrain mapping and object identification.
Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research.
Herring arrives earlier in the Wadden Sea due to climate change
Due to the changing climate, young herring arrive in the Wadden Sea earlier and earlier in spring.
With hybrid brains, these mice smell like a rat
Mice lacking an olfactory system have had their sense of smell restored with neurons from rats, the first time scientists have successfully integrated the sensory apparatus of one species into another.
Estimating emissions potential of decommissioned gas wells from shale samples
Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. Researchers have now developed a new tool that can estimate the emission potential of shale wells after they are no longer active.
Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
A recent study utilized ground-based instruments to measure solar-induced fluorescence (SIF) that reflect plant health and photosynthesis.
The longer spilled oil lingers in freshwater, the more persistent compounds it produces
Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. The longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment.
Warming Arctic reduces dust levels in parts of the planet
Dust can have a huge impact on local air quality, food security, energy supply and public health. Previous studies have found that dust levels are decreasing across India, particularly northern India, the Persian Gulf Coast and much of the Middle East, but the reason has remained unclear. Researchers found that the decrease in dust can be attributed to the Arctic warming much faster than the rest of the planet, a phenomenon known as Arctic amplification. This process destabilizes the jet stream and changes storm tracks and wind patterns over the major sources of dust in West and South Asia.
Identifying a new liver defender: The role of resident macrophages
Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as 'sentinel macrophages,' they are activated by isoallo-lithocholic acid. This finding holds promise for developing preventive and therapeutic strategies for liver chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH), by enhancing the function of these macrophages to mitigate inflammation and improve treatment efficacy.
Synthetic droplets cause a stir in the primordial soup
Our bodies are made up of trillions of different cells, each fulfilling their own unique function to keep us alive. How do cells move around inside these extremely complicated systems? How do they know where to go? And how did they get so complicated to begin with? Simple yet profound questions like these are at the heart of curiosity-driven basic research, which focuses on the fundamental principles of natural phenomena.
Key to efficient and stable organic solar cells
A team of researchers has made a significant breakthrough in the field of organic photovoltaics.
A new study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Freeze casting: A guide to creating hierarchically structured materials
Freeze casting is an elegant, cost-effective manufacturing technique to produce highly porous materials with custom-designed hierarchical architectures, well-defined pore orientation, and multifunctional surface structures. Freeze-cast materials are suitable for many applications, from biomedicine to environmental engineering and energy technologies.
How do birds flock? Researchers do the math to reveal previously unknown aerodynamic phenomenon
How do birds fly in a coordinated and seemingly effortless fashion? Part of the answer lies in precise, and previously unknown, aerodynamic interactions, reports a team of mathematicians. Its breakthrough broadens our understanding of wildlife, including fish, who move in schools, and could have applications in transportation and energy.
IRIS beamline at BESSY II extended with nanomicroscopy
The IRIS infrared beamline at the BESSY II storage ring now offers a fourth option for characterizing materials, cells and even molecules on different length scales. The team has extended the IRIS beamline with an end station for nanospectroscopy and nanoimaging that enables spatial resolutions down to below 30 nanometers. The instrument is also available to external user groups.
Researchers have pioneered a breakthrough in ferroelectric material development. They've engineered a novel displacement-type ferroelectric material boasting remarkable dielectric properties. Their achievement includes the successful synthesis of rubidium niobate (RbNbO3), a compound previously deemed challenging to produce under pressures exceeding 40,000 atmospheres. Additionally, they characterized how polarization changes across a wide temperature range during phase transitions. This breakthrough can lead to new design guidelines for ferroelectric materials.
AI in medicine: The causality frontier
Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.
How electric vehicle drivers can escape range anxiety
Two of the biggest challenges faced by new and potential electric vehicle (EV) drivers are range anxiety and speed of charging, but these shouldn't have to be challenges at all. Researchers discovered that a change in refueling mindset, rather than improving the size or performance of the battery, could be the answer to these concerns.
Advanced cell atlas opens new doors in biomedical research
Researchers have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease.
Using AI to improve diagnosis of rare genetic disorders
Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators are trying to make the process more efficient using artificial intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially causative variants for Mendelian disorders.
The secret to saving old books could be gluten-free glues
'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Maternal grandmothers' support buffers children against the impacts of adversity
A study shows that investment by maternal grandmothers can improve the well-being of grandchildren who have faced adversities in life. The positive effects can last well into adulthood.
Circadian rhythms can influence drugs' effectiveness
Researchers discovered that more than 300 liver genes are under circadian control: Circadian variations affect how much of a drug is available and how effectively the body can break it down.
How immune cells communicate to fight viruses
Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers have now developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors.
National trial safely scaled back prescribing of a powerful antipsychotic for the elderly
Warning letters can safely cut prescribing of a powerful but risky antipsychotic, according to a new study. Researchers used Medicare data to study the effects of the letters on hundreds of thousands of older adults with dementia. They found a significant and lasting reduction in prescribing but no signs of adverse effects on patient health.